TUESDAY, June 29, 2021 (HealthDay News) — Components of nonpharmacological interventions may be effective for treating pediatric migraines, according to a review published recently in Pediatrics.
Helen Koechlin, Ph.D., of the University of Basel in Switzerland, and colleagues conducted a systematic review and network meta-analysis to investigate whether non-pharmacological treatments are more effective than a waiting list for children with migraines. Data was included from 12 studies with 576 participants.
The researchers found that self-administered treatments, biofeedback relaxation, psychological treatment, and psychological placebos were significantly more effective than waiting list when interventions were grouped based on the similarity of the treatment components; effect sizes ranged from standardized mean differences of 1.14 (95 percent confidence interval, 0.09 to 2.19) to 1.44 (95 percent confidence interval, 0.26 to 2.62) for long-term psychological placebos and short-term self-control, respectively. administered treatments. However, none of the interventions were significantly more effective than waiting list control when all interventions were examined separately, mainly due to a lack of statistical power.
“When analyzed in broad nodes and pooled based on similarity of treatment components, these interventions revealed large and presumably clinically meaningful effect sizes for some patients,” the authors write. “However, the more detailed analysis (i.e., the split approach) suggested that some effects should be carefully considered because they are based on small studies.”
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